Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells

In mammalian cells genes that are in close proximity can be transcriptionally coupled: silencing or activating one gene can affect its neighbors. Understanding these dynamics is important for natural processes, such as heterochromatin spreading during development and aging, and when designing synthe...

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Detalles Bibliográficos
Autores principales: Lensch, Sarah, Herschl, Michael H, Ludwig, Connor H, Sinha, Joydeb, Hinks, Michaela M, Mukund, Adi, Fujimori, Taihei, Bintu, Lacramioara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9183234/
https://www.ncbi.nlm.nih.gov/pubmed/35678392
http://dx.doi.org/10.7554/eLife.75115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9183234/
https://www.ncbi.nlm.nih.gov/pubmed/35678392
http://dx.doi.org/10.7554/eLife.75115

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