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Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells
In mammalian cells genes that are in close proximity can be transcriptionally coupled: silencing or activating one gene can affect its neighbors. Understanding these dynamics is important for natural processes, such as heterochromatin spreading during development and aging, and when designing synthe...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9183234/ https://www.ncbi.nlm.nih.gov/pubmed/35678392 http://dx.doi.org/10.7554/eLife.75115 |