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Bayesian machine learning analysis of single-molecule fluorescence colocalization images

Multi-wavelength single-molecule fluorescence colocalization (CoSMoS) methods allow elucidation of complex biochemical reaction mechanisms. However, analysis of CoSMoS data is intrinsically challenging because of low image signal-to-noise ratios, non-specific surface binding of the fluorescent molec...

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Detalles Bibliográficos
Autores principales: Ordabayev, Yerdos A, Friedman, Larry J, Gelles, Jeff, Theobald, Douglas L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9183235/
https://www.ncbi.nlm.nih.gov/pubmed/35319463
http://dx.doi.org/10.7554/eLife.73860