Automated immunofluorescence analysis for sensitive and precise dystrophin quantification in muscle biopsies

AIMS: Dystrophin, the protein product of the DMD gene, plays a critical role in muscle integrity by stabilising the sarcolemma during contraction and relaxation. The DMD gene is vulnerable to a variety of mutations that may cause complete loss, depletion or truncation of the protein, leading to Duch...

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Detalles Bibliográficos
Autores principales: Vetter, Tatyana A., Nicolau, Stefan, Bradley, Adrienne J., Frair, Emma C., Flanigan, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184255/
https://www.ncbi.nlm.nih.gov/pubmed/34847621
http://dx.doi.org/10.1111/nan.12785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184255/
https://www.ncbi.nlm.nih.gov/pubmed/34847621
http://dx.doi.org/10.1111/nan.12785

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