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Targeting NMDA receptors in neuropsychiatric disorders by drug screening on human neurons derived from pluripotent stem cells

NMDA receptors (NMDARs), a prominent subtype of glutamatergic receptors, are implicated in the pathogenesis and development of neuropsychiatric disorders such as epilepsy, intellectual disability, autism spectrum disorder, and schizophrenia, and are therefore a potential therapeutic target in treati...

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Detalles Bibliográficos
Autores principales: Zhang, Wenbo, Ross, P. Joel, Ellis, James, Salter, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184461/
https://www.ncbi.nlm.nih.gov/pubmed/35680847
http://dx.doi.org/10.1038/s41398-022-02010-z