A high-content neuron imaging assay demonstrates inhibition of prion disease-associated neurotoxicity by an anti-prion protein antibody

There is an urgent need to develop disease-modifying therapies to treat neurodegenerative diseases which pose increasing challenges to global healthcare systems. Prion diseases, although rare, provide a paradigm to study neurodegenerative dementias as similar disease mechanisms involving propagation...

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Detalles Bibliográficos
Autores principales: Reilly, Madeleine, Benilova, Iryna, Khalili-Shirazi, Azadeh, Schmidt, Christian, Ahmed, Parvin, Yip, Daniel, Jat, Parmjit S., Collinge, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184462/
https://www.ncbi.nlm.nih.gov/pubmed/35680944
http://dx.doi.org/10.1038/s41598-022-13455-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184462/
https://www.ncbi.nlm.nih.gov/pubmed/35680944
http://dx.doi.org/10.1038/s41598-022-13455-z

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