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A high-content neuron imaging assay demonstrates inhibition of prion disease-associated neurotoxicity by an anti-prion protein antibody
There is an urgent need to develop disease-modifying therapies to treat neurodegenerative diseases which pose increasing challenges to global healthcare systems. Prion diseases, although rare, provide a paradigm to study neurodegenerative dementias as similar disease mechanisms involving propagation...
Autores principales: | Reilly, Madeleine, Benilova, Iryna, Khalili-Shirazi, Azadeh, Schmidt, Christian, Ahmed, Parvin, Yip, Daniel, Jat, Parmjit S., Collinge, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184462/ https://www.ncbi.nlm.nih.gov/pubmed/35680944 http://dx.doi.org/10.1038/s41598-022-13455-z |
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