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Functional and morphologic dysfunctions in the airways of rats submitted to an experimental model of obesity-exacerbated asthma

The obesity-exacerbated asthma phenotype is characterized by more severe asthma symptoms and glucocorticoid resistance. The aim of this study was to standardize an obesity-exacerbated asthma model by a high glycemic level index (HGLI) diet and ovalbumin (OVA) sensitization and challenges in Wistar r...

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Detalles Bibliográficos
Autores principales: Ferreira, Sarah Rebeca Dantas, Pessoa, Rayane Fernandes, Figueiredo, Indyra Alencar Duarte, Lima, João Pedro Moura, de Moura, Thayna Maria Costa Fernandes, Bezerra, Cleyton Oliveira, de Oliveira Martins, Alissa Maria, de Carvalho, Leila Moreira, Madruga, Marta Suely, Cavalcante, Hassler Clementino, de Souza Aquino, Jailane, de Brito Alves, José Luiz, Alves, Adriano Francisco, Vasconcelos, Luiz Henrique César, de Andrade Cavalcante, Fabiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184493/
https://www.ncbi.nlm.nih.gov/pubmed/35681069
http://dx.doi.org/10.1038/s41598-022-13551-0