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A Catharanthus roseus Fe(II)/α-ketoglutarate-dependent dioxygenase catalyzes a redox-neutral reaction responsible for vindolinine biosynthesis

The Madagascar’s periwinkle is the model plant for studies of plant specialized metabolism and monoterpenoid indole alkaloids (MIAs), and an important source for the anticancer medicine vinblastine. The elucidation of entire 28-step biosynthesis of vinblastine allowed further investigations for the...

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Detalles Bibliográficos
Autores principales: Eng, Jasmine Ga May, Shahsavarani, Mohammadamin, Smith, Daniel Patrick, Hájíček, Josef, De Luca, Vincenzo, Qu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184523/
https://www.ncbi.nlm.nih.gov/pubmed/35680936
http://dx.doi.org/10.1038/s41467-022-31100-1