Cargando…

Dynamic mRNA degradome analyses indicate a role of histone H3K4 trimethylation in association with meiosis-coupled mRNA decay in oocyte aging

A decrease in oocyte developmental potential is a major obstacle for successful pregnancy in women of advanced age. However, the age-related epigenetic modifications associated with dynamic transcriptome changes, particularly meiotic maturation-coupled mRNA clearance, have not been adequately charac...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yun-Wen, Li, Sen, Zheng, Wei, Li, Yan-Chu, Chen, Lu, Zhou, Yong, Deng, Zuo-Qi, Lin, Ge, Fan, Heng-Yu, Sha, Qian-Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184541/
https://www.ncbi.nlm.nih.gov/pubmed/35680896
http://dx.doi.org/10.1038/s41467-022-30928-x