Selectivity and Maximum Response of Vibegron and Mirabegron for β(3)-Adrenergic Receptors

BACKGROUND: The β(3)-adrenergic agonists vibegron and mirabegron have shown favorable safety profiles and efficacy for the treatment of overactive bladder. However, β-adrenergic receptors are also found outside the bladder, which could lead to off-target activity. OBJECTIVE: This study assessed the...

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Detalles Bibliográficos
Autores principales: Brucker, Benjamin M., King, Jennifer, Mudd, Paul N., McHale, Kimberly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184556/
https://www.ncbi.nlm.nih.gov/pubmed/35693456
http://dx.doi.org/10.1016/j.curtheres.2022.100674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184556/
https://www.ncbi.nlm.nih.gov/pubmed/35693456
http://dx.doi.org/10.1016/j.curtheres.2022.100674

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