A conditional counterselectable Piga knockout in mouse embryonic stem cells for advanced genome writing applications

Overwriting counterselectable markers is an efficient strategy for removing wild-type DNA or replacing it with payload DNA of interest. Currently, one bottleneck of efficient genome engineering in mammals is the shortage of counterselectable (negative selection) markers that work robustly without af...

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Detalles Bibliográficos
Autores principales: Zhang, Weimin, Brosh, Ran, McCulloch, Laura H., Zhu, Yinan, Ashe, Hannah, Ellis, Gwen, Camellato, Brendan R., Kim, Sang Yong, Maurano, Matthew T., Boeke, Jef D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184564/
https://www.ncbi.nlm.nih.gov/pubmed/35692632
http://dx.doi.org/10.1016/j.isci.2022.104438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184564/
https://www.ncbi.nlm.nih.gov/pubmed/35692632
http://dx.doi.org/10.1016/j.isci.2022.104438

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