Nt5e deficiency does not affect post-stroke inflammation and lesion size in a murine ischemia/reperfusion stroke model

Extracellular ATP released to the ischemic brain parenchyma is quickly metabolized by ectonucleotidases. Among them, the ecto-5′-nucleotidase CD73 encoded by Nt5e generates immunosuppressive adenosine. Genetic deletion of Nt5e led to increased infarct size in the murine photothrombotic stroke model....

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Detalles Bibliográficos
Autores principales: Schädlich, Ines Sophie, Schnapauff, Oliver, Pöls, Lennart, Schrader, Jürgen, Tolosa, Eva, Rissiek, Björn, Magnus, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184566/
https://www.ncbi.nlm.nih.gov/pubmed/35692634
http://dx.doi.org/10.1016/j.isci.2022.104470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184566/
https://www.ncbi.nlm.nih.gov/pubmed/35692634
http://dx.doi.org/10.1016/j.isci.2022.104470

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