Lipase regulation of cellular fatty acid homeostasis as a Parkinson’s disease therapeutic strategy

Synucleinopathy (Parkinson’s disease (PD); Lewy body dementia) disease-modifying treatments represent a huge unmet medical need. Although the PD-causing protein α-synuclein (αS) interacts with lipids and fatty acids (FA) physiologically and pathologically, targeting FA homeostasis for therapeutics i...

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Detalles Bibliográficos
Autores principales: Fanning, Saranna, Cirka, Haley, Thies, Jennifer L., Jeong, Jooyoung, Niemi, Sarah M., Yoon, Joon, Ho, Gary P. H., Pacheco, Julian A., Dettmer, Ulf, Liu, Lei, Clish, Clary B., Hodgetts, Kevin J., Hutchinson, John N., Muratore, Christina R., Caldwell, Guy A., Caldwell, Kim A., Selkoe, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184586/
https://www.ncbi.nlm.nih.gov/pubmed/35680956
http://dx.doi.org/10.1038/s41531-022-00335-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184586/
https://www.ncbi.nlm.nih.gov/pubmed/35680956
http://dx.doi.org/10.1038/s41531-022-00335-6

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