New free radical-initiated peptide sequencing (FRIPS) mass spectrometry reagent with high conjugation efficiency enabling single-step peptide sequencing

A newly designed TEMPO-FRIPS reagent, 4-(2,2,6,6-tetramethylpiperidine-1-oxyl) methyl benzyl succinic acid N-hydroxysuccinimide ester or p-TEMPO–Bn–Sc–NHS, was synthesized to achieve single-step free radical-initiated peptide sequencing mass spectrometry (FRIPS MS) for a number of model peptides, in...

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Detalles Bibliográficos
Autores principales: Lee, Sang Tak, Park, Hyemi, Jang, Inae, Lee, Choong Sik, Moon, Bongjin, Oh, Han Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184593/
https://www.ncbi.nlm.nih.gov/pubmed/35680949
http://dx.doi.org/10.1038/s41598-022-13624-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184593/
https://www.ncbi.nlm.nih.gov/pubmed/35680949
http://dx.doi.org/10.1038/s41598-022-13624-0

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