Small molecule targeting FOXM1 DNA binding domain exhibits anti-tumor activity in ovarian cancer

FOXM1 is a potent oncogenic transcription factor essential for cancer initiation, progression, and drug resistance. FOXM1 regulatory network is a major predictor of adverse outcomes in various human cancers. Inhibition of FOXM1 transcription factor function is a potential strategy in cancer treatmen...

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Detalles Bibliográficos
Autores principales: Zhang, Zaixin, Xue, Si-tu, Gao, Yan, Li, Yingwei, Zhou, Ziying, Wang, Jing, Li, Zhuorong, Liu, Zhaojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184618/
https://www.ncbi.nlm.nih.gov/pubmed/35680842
http://dx.doi.org/10.1038/s41420-022-01070-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184618/
https://www.ncbi.nlm.nih.gov/pubmed/35680842
http://dx.doi.org/10.1038/s41420-022-01070-w

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