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Small molecule targeting FOXM1 DNA binding domain exhibits anti-tumor activity in ovarian cancer
FOXM1 is a potent oncogenic transcription factor essential for cancer initiation, progression, and drug resistance. FOXM1 regulatory network is a major predictor of adverse outcomes in various human cancers. Inhibition of FOXM1 transcription factor function is a potential strategy in cancer treatmen...
Autores principales: | Zhang, Zaixin, Xue, Si-tu, Gao, Yan, Li, Yingwei, Zhou, Ziying, Wang, Jing, Li, Zhuorong, Liu, Zhaojian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184618/ https://www.ncbi.nlm.nih.gov/pubmed/35680842 http://dx.doi.org/10.1038/s41420-022-01070-w |
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