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Efferocytosis requires periphagosomal Ca(2+)-signaling and TRPM7-mediated electrical activity

Efficient clearance of apoptotic cells by phagocytosis, also known as efferocytosis, is fundamental to developmental biology, organ physiology, and immunology. Macrophages use multiple mechanisms to detect and engulf apoptotic cells, but the signaling pathways that regulate the digestion of the apop...

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Detalles Bibliográficos
Autores principales: Schappe, Michael S., Stremska, Marta E., Busey, Gregory W., Downs, Taylor K., Seegren, Philip V., Mendu, Suresh K., Flegal, Zachary, Doyle, Catherine A., Stipes, Eric J., Desai, Bimal N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184625/
https://www.ncbi.nlm.nih.gov/pubmed/35680919
http://dx.doi.org/10.1038/s41467-022-30959-4