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Efferocytosis requires periphagosomal Ca(2+)-signaling and TRPM7-mediated electrical activity
Efficient clearance of apoptotic cells by phagocytosis, also known as efferocytosis, is fundamental to developmental biology, organ physiology, and immunology. Macrophages use multiple mechanisms to detect and engulf apoptotic cells, but the signaling pathways that regulate the digestion of the apop...
Autores principales: | Schappe, Michael S., Stremska, Marta E., Busey, Gregory W., Downs, Taylor K., Seegren, Philip V., Mendu, Suresh K., Flegal, Zachary, Doyle, Catherine A., Stipes, Eric J., Desai, Bimal N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184625/ https://www.ncbi.nlm.nih.gov/pubmed/35680919 http://dx.doi.org/10.1038/s41467-022-30959-4 |
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