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Malaria oocysts require circumsporozoite protein to evade mosquito immunity

Malaria parasites are less vulnerable to mosquito immune responses once ookinetes transform into oocysts, facilitating parasite development in the mosquito. However, the underlying mechanisms of oocyst resistance to mosquito defenses remain unclear. Here, we show that circumsporozoite protein (CSP)...

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Detalles Bibliográficos
Autores principales: Zhu, Feng, Zheng, Hong, Chen, Suilin, Zhang, Kun, Qin, Xin, Zhang, Jingru, liu, Taiping, Fan, Yongling, Wang, Liting, Li, Xiaoxu, Zhang, Jian, Xu, Wenyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184642/
https://www.ncbi.nlm.nih.gov/pubmed/35680915
http://dx.doi.org/10.1038/s41467-022-30988-z