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Integration of Transcriptomics and Metabolomics Reveals the Antitumor Mechanism Underlying Tadalafil in Colorectal Cancer

The potential role of tadalafil, a PDE5 inhibitor, in anticancer activity and prolonged survival has been proposed. However, the systematic effects of tadalafil in colorectal cancer were not fully understood. In this study, we assessed the anti-tumor activity of tadalafil in human colorectal cancer...

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Detalles Bibliográficos
Autores principales: Zhao, Pan, Shen, Yao, Li, Mengyang, Dan, Hanjun, Zhao, Zhiming, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184725/
https://www.ncbi.nlm.nih.gov/pubmed/35694253
http://dx.doi.org/10.3389/fphar.2022.793499