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Multi-omics profiling of single nuclei from frozen archived postmortem human pituitary tissue

Concomitant profiling of transcriptome and chromatin accessibility in isolated nuclei can reveal gene regulatory control mechanisms in health and disease. We report a single nucleus multi-omics analysis protocol optimized for frozen archived postmortem human pituitaries that is also effective for fr...

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Detalles Bibliográficos
Autores principales:	Mendelev, Natalia, Zamojski, Michel, Amper, Mary Anne S., Cheng, Wan Sze, Pincas, Hanna, Nair, Venugopalan D., Zaslavsky, Elena, Sealfon, Stuart C., Ruf-Zamojski, Frederique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184808/ https://www.ncbi.nlm.nih.gov/pubmed/35693209 http://dx.doi.org/10.1016/j.xpro.2022.101446

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