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SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2(ZYG11B) activity

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causal pathogen of the ongoing global pandemic of coronavirus disease 2019 (COVID-19). Loss of smell and taste are symptoms of COVID-19, and may be related to cilia dysfunction. Here, we found that the SARS-CoV-2 ORF10 increases the...

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Detalles Bibliográficos
Autores principales: Wang, Liying, Liu, Chao, Yang, Bo, Zhang, Haotian, Jiao, Jian, Zhang, Ruidan, Liu, Shujun, Xiao, Sai, Chen, Yinghong, Liu, Bo, Ma, Yanjie, Duan, Xuefeng, Guo, Yueshuai, Guo, Mengmeng, Wu, Bingbing, Wang, Xiangdong, Huang, Xingxu, Yang, Haitao, Gui, Yaoting, Fang, Min, Zhang, Luo, Duo, Shuguang, Guo, Xuejiang, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184850/
https://www.ncbi.nlm.nih.gov/pubmed/35674692
http://dx.doi.org/10.1083/jcb.202108015