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Impact of imatinib administration on the mouse ovarian follicle count and levels of intra-ovarian proteins related to follicular quality

OBJECTIVE: The impact of imatinib, a tyrosine kinase inhibitor, on ovarian follicles and several proteins related to follicular function and apoptosis was investigated in mice. METHODS: Saline, cyclophosphamide (Cp; 50 or 75 mg/kg), or imatinib (7.5 or 15 mg/kg) was injected once intraperitoneally i...

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Detalles Bibliográficos
Autores principales: Kim, Se Jeong, Kim, Tae Eun, Jee, Byung Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Reproductive Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184883/
https://www.ncbi.nlm.nih.gov/pubmed/35698771
http://dx.doi.org/10.5653/cerm.2022.05218