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Structure and surface analyses of a newly synthesized acyl thiourea derivative along with its in silico and in vitro investigations for RNR, DNA binding, urease inhibition and radical scavenging activities

N-((4-Acetylphenyl)carbamothioyl)-2,4-dichlorobenzamide (4) was synthesized by the treatment of 2,4-dichlorobenzoyl chloride with potassium thiocyanate in a 1 : 1 molar ratio in dry acetone to afford the 2,4-dichlorobenzoyl isothiocyanate in situ which on reaction with acetyl aniline furnished (4) i...

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Detalles Bibliográficos
Autores principales: Khalid, Aqsa, Arshad, Nasima, Channar, Pervaiz Ali, Saeed, Aamer, Mir, Muhammad Ismail, Abbas, Qamar, Ejaz, Syeda Abida, Hökelek, Tuncer, Saeed, Amna, Tehzeeb, Arfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185314/
https://www.ncbi.nlm.nih.gov/pubmed/35755589
http://dx.doi.org/10.1039/d2ra03160d