Cell-Based Delivery Approaches for DNA-Binding Domains to the Central Nervous System

Advancements in programmable DNA-Binding Proteins (DBDs) that target the genome, such as zinc fingers, transcription activator-like effectors, and Cas9, have broadened drug target design beyond traditional protein substrates. Effective delivery methodologies remain a major barrier in targeting the c...

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Detalles Bibliográficos
Autores principales: Deng, Peter, Halmai, Julian, Waldo, Jennifer J., Fink, Kyle D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185769/
https://www.ncbi.nlm.nih.gov/pubmed/33998992
http://dx.doi.org/10.2174/1570159X19666210517144044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185769/
https://www.ncbi.nlm.nih.gov/pubmed/33998992
http://dx.doi.org/10.2174/1570159X19666210517144044

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