Cargando…
Cell-Based Delivery Approaches for DNA-Binding Domains to the Central Nervous System
Advancements in programmable DNA-Binding Proteins (DBDs) that target the genome, such as zinc fingers, transcription activator-like effectors, and Cas9, have broadened drug target design beyond traditional protein substrates. Effective delivery methodologies remain a major barrier in targeting the c...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Bentham Science Publishers
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185769/ https://www.ncbi.nlm.nih.gov/pubmed/33998992 http://dx.doi.org/10.2174/1570159X19666210517144044 |