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Sodium(+)/taurocholate cotransporting polypeptide as target therapy for liver fibrosis

OBJECTIVE: Sodium(+)/ taurocholate cotransporting polypeptide (NTCP) is a membrane transporter affecting the enterohepatic circulation of bile acids (BAs). We aimed to evaluate NTCP’s roles in humans and animal models of liver fibrosis (LF). DESIGN: Primary hepatic stellate cells (pHSCs) isolated fr...

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Detalles Bibliográficos
Autores principales: Salhab, Ahmad, Amer, Johnny, Lu, Yinying, Safadi, Rifaat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185811/
https://www.ncbi.nlm.nih.gov/pubmed/34266968
http://dx.doi.org/10.1136/gutjnl-2020-323345