The human liver microenvironment shapes the homing and function of CD4(+) T-cell populations

OBJECTIVE: Tissue-resident memory T cells (T(RM)) are vital immune sentinels that provide protective immunity. While hepatic CD8(+) T(RM) have been well described, little is known about the location, phenotype and function of CD4(+) T(RM). DESIGN: We used multiparametric flow cytometry, histological...

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Detalles Bibliográficos
Autores principales: Wiggins, Benjamin G, Pallett, Laura J, Li, Xiaoyan, Davies, Scott P, Amin, Oliver E, Gill, Upkar S, Kucykowicz, Stephanie, Patel, Arzoo M, Aliazis, Konstantinos, Liu, Yuxin S, Reynolds, Gary M, Davidson, Brian R, Gander, Amir, Luong, Tu Vinh, Hirschfield, Gideon M, Kennedy, Patrick T F, Huang, Yuehua, Maini, Mala K, Stamataki, Zania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185819/
https://www.ncbi.nlm.nih.gov/pubmed/34548339
http://dx.doi.org/10.1136/gutjnl-2020-323771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185819/
https://www.ncbi.nlm.nih.gov/pubmed/34548339
http://dx.doi.org/10.1136/gutjnl-2020-323771

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