An enhanced antioxidant strategy of astaxanthin encapsulated in ROS-responsive nanoparticles for combating cisplatin-induced ototoxicity

BACKGROUND: Excessive accumulation of reactive oxygen species (ROS) has been documented as the crucial cellular mechanism of cisplatin-induced ototoxicity. However, numerous antioxidants have failed in clinical studies partly due to inefficient drug delivery to the cochlea. A drug delivery system is...

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Detalles Bibliográficos
Autores principales: Gu, Jiayi, Wang, Xueling, Chen, Yuming, Xu, Ke, Yu, Dehong, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185887/
https://www.ncbi.nlm.nih.gov/pubmed/35689218
http://dx.doi.org/10.1186/s12951-022-01485-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185887/
https://www.ncbi.nlm.nih.gov/pubmed/35689218
http://dx.doi.org/10.1186/s12951-022-01485-8

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