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KCNN4 may weaken anti-tumor immune response via raising Tregs and diminishing resting mast cells in clear cell renal cell carcinoma

BACKGROUND: Studies over the past decade have shown that competitive endogenous RNA (ceRNA) plays an essential role in the tumorigenesis and progression of clear cell renal cell carcinoma (ccRCC). Meanwhile, immune checkpoint blocker is gradually moving towards the first-line treatment of ccRCC. Hen...

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Detalles Bibliográficos
Autores principales: Cui, Yankang, Shen, Tianyi, Xu, Feng, Zhang, Jing, Wang, Yuhao, Wu, Jiajin, Bu, Hengtao, Fu, Dian, Fang, Bo, Lv, Huichen, Wang, Suchun, Shi, Changjie, Liu, Bianjiang, He, Haowei, Tang, Hao, Ge, Jingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9185981/
https://www.ncbi.nlm.nih.gov/pubmed/35689211
http://dx.doi.org/10.1186/s12935-022-02626-7