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Affecting AMPA Receptor Biophysical Gating Properties with Negative Allosteric Modulators

Glutamatergic chemical synapses mediate excitatory neurotransmission by the ion flow through α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-type glutamate receptors in the central nervous system (CNS). AMPA receptor-mediated synaptic transmission abnormalities may play a role in neurol...

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Detalles Bibliográficos
Autores principales: Qneibi, Mohammad, Hawash, Mohammad, Jaradat, Nidal, Bdir, Sosana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186005/
https://www.ncbi.nlm.nih.gov/pubmed/35687302
http://dx.doi.org/10.1007/s12035-022-02913-4