Folic acid deficiency increases sensitivity to DNA damage by glucose and methylglyoxal

Type 2 diabetes (T2D) is associated with elevated frequencies of micronuclei (MNi) and other DNA damage biomarkers. Interestingly, individuals with T2D are more likely to be deficient in micronutrients (folic acid, pyridoxal-phosphate, cobalamin) that play key roles in one-carbon metabolism and main...

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Detalles Bibliográficos
Autores principales: Donnellan, Leigh, Simpson, Bradley S, Dhillon, Varinderpal S, Costabile, Maurizio, Fenech, Michael, Deo, Permal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Manuscripts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186029/
https://www.ncbi.nlm.nih.gov/pubmed/35079805
http://dx.doi.org/10.1093/mutage/geac003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186029/
https://www.ncbi.nlm.nih.gov/pubmed/35079805
http://dx.doi.org/10.1093/mutage/geac003

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