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Are polygenic risk scores ready for the cancer clinic?—a perspective

To realize the goals of precision medicine in complex disease, discriminative clinical risk models are needed. One approach that has been proposed is polygenic risk scores (PRSs). PRSs incorporate information about inherited genetic risk for cancer, specifically those genetic variants that are commo...

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Detalles Bibliográficos
Autores principales: Klein, Robert J., Gümüş, Zeynep H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186162/
https://www.ncbi.nlm.nih.gov/pubmed/35693291
http://dx.doi.org/10.21037/tlcr-21-698