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Are polygenic risk scores ready for the cancer clinic?—a perspective
To realize the goals of precision medicine in complex disease, discriminative clinical risk models are needed. One approach that has been proposed is polygenic risk scores (PRSs). PRSs incorporate information about inherited genetic risk for cancer, specifically those genetic variants that are commo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186162/ https://www.ncbi.nlm.nih.gov/pubmed/35693291 http://dx.doi.org/10.21037/tlcr-21-698 |