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Dl-3-n-butylphthalide attenuates myocardial ischemia reperfusion injury by suppressing oxidative stress and regulating cardiac mitophagy via the PINK1/Parkin pathway in rats

BACKGROUND: Acute myocardial infarction (AMI) is one of the leading causes of mortality worldwide. Undesirable myocardial damage may occur during reperfusion of the ischemic myocardium, and this is known as “ischemic reperfusion injury” (IRI). Currently, there are few effective drugs to alleviate IR...

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Detalles Bibliográficos
Autores principales: Zhang, Dongqin, Zheng, Nan, Fu, Xiaoli, Shi, Jian, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186216/
https://www.ncbi.nlm.nih.gov/pubmed/35693588
http://dx.doi.org/10.21037/jtd-22-585