Cargando…
The transformation of atrial fibroblasts into myofibroblasts is promoted by trimethylamine N-oxide via the Wnt3a/β-catenin signaling pathway
BACKGROUND: Atrial fibrosis is an important pathophysiological mechanism in the development and maintenance of atrial fibrillation. Trimethylamine N-oxide (TMAO) is one of the most widely studied microbial metabolites involved in the promotion of cardiac fibrosis. TMAO promotes phenotypic transforma...
Autores principales: | Yang, Wentao, Zhao, Qing, Yao, Minghui, Li, Xiangdong, Shan, Zhaoliang, Wang, Yutang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186223/ https://www.ncbi.nlm.nih.gov/pubmed/35693618 http://dx.doi.org/10.21037/jtd-22-475 |
Ejemplares similares
-
MicroRNA-499-5p inhibits transforming growth factor-β1-induced Smad2 signaling pathway and suppresses fibroblast proliferation and collagen synthesis in rat by targeting TGFβ-R1
por: Zhao, Qing, et al.
Publicado: (2023) -
Predictive value of pre-procedural N-terminal pro-B-type natriuretic peptide level for atrial fibrillation recurrence after radiofrequency catheter ablation
por: Zhao, Qing, et al.
Publicado: (2023) -
The prognostic significance of left atrial appendage peak flow velocity in the recurrence of persistent atrial fibrillation following first radiofrequency catheter ablation
por: Yang, Wentao, et al.
Publicado: (2021) -
Hydrogen sulphide suppresses human atrial fibroblast proliferation and transformation to myofibroblasts
por: Sheng, Jingwei, et al.
Publicado: (2013) -
Trimethylamine N-oxide in atrial fibrillation progression
por: Büttner, Petra, et al.
Publicado: (2020)