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RBM33 directs the nuclear export of transcripts containing GC-rich elements

Although splicing is a major driver of RNA nuclear export, many intronless RNAs are efficiently exported to the cytoplasm through poorly characterized mechanisms. For example, GC-rich sequences promote nuclear export in a splicing-independent manner, but how GC content is recognized and coupled to n...

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Detalles Bibliográficos
Autores principales: Thomas, Anu, Rehfeld, Frederick, Zhang, He, Chang, Tsung-Cheng, Goodarzi, Mohammad, Gillet, Frank, Mendell, Joshua T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186391/
https://www.ncbi.nlm.nih.gov/pubmed/35589130
http://dx.doi.org/10.1101/gad.349456.122