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Multiomics analysis of the NAD(+)–PARP1 axis reveals a role for site-specific ADP-ribosylation in splicing in embryonic stem cells
The differentiation of embryonic stem cells (ESCs) into a lineage-committed state is a dynamic process involving changes in cellular metabolism, epigenetic modifications, post-translational modifications, gene expression, and RNA processing. Here we integrated data from metabolomic, proteomic, and t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186393/ https://www.ncbi.nlm.nih.gov/pubmed/35654456 http://dx.doi.org/10.1101/gad.349335.121 |