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Dysregulation of the cGAS-STING Pathway in Monogenic Autoinflammation and Lupus
One of the oldest mechanisms of immune defense against pathogens is through detection of foreign DNA. Since human DNA is compartmentalized into the nucleus, its presence in the cytosol heralds a potential threat. The cGAS-STING pathway is one of the most important cytosolic DNA sensing pathways and...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186411/ https://www.ncbi.nlm.nih.gov/pubmed/35693769 http://dx.doi.org/10.3389/fimmu.2022.905109 |