Rational Framework for the Design of Trp- and Arg-Rich Peptide Antibiotics Against Multidrug-Resistant Bacteria

The threat of antibiotic resistance warrants the discovery of agents with novel antimicrobial mechanisms. Antimicrobial peptides (AMPs) directly disrupting bacterial membranes may overcome resistance to traditional antibiotics. AMP development for clinical use has been mostly limited to topical appl...

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Detalles Bibliográficos
Autores principales: Xiang, Wenyu, Clemenza, Patrice, Klousnitzer, Jessie, Chen, Jespar, Qin, Weiheng, Tristram-Nagle, Stephanie, Doi, Yohei, Di, Y. Peter, Deslouches, Berthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186412/
https://www.ncbi.nlm.nih.gov/pubmed/35694289
http://dx.doi.org/10.3389/fmicb.2022.889791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186412/
https://www.ncbi.nlm.nih.gov/pubmed/35694289
http://dx.doi.org/10.3389/fmicb.2022.889791

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