miR-451a targeting IL-6R activates JAK2/STAT3 pathway, thus regulates proliferation and apoptosis of multiple myeloma cells

OBJECTIVES: To investigate the effects of miR-451a targeting interleukin-6 (IL-6) on the proliferation and apoptosis of multiple myeloma (MM) cells and its potential mechanism via JAK2/STAT3 pathway. METHODS: mRNA expression of miR-451a and IL-6R in the plasma of patients with MM and normal controls...

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Detalles Bibliográficos
Autores principales: Xu, Lingling, Yao, Yuning, Lu, Ting, Jiang, Libo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Society of Musculoskeletal and Neuronal Interactions 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186451/
https://www.ncbi.nlm.nih.gov/pubmed/35642704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186451/
https://www.ncbi.nlm.nih.gov/pubmed/35642704

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