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Expansion of cytotoxic tissue-resident CD8(+) T cells and CCR6(+)CD161(+) CD4(+) T cells in the nasal mucosa following mRNA COVID-19 vaccination

Vaccines against SARS-CoV-2 have shown high efficacy in clinical trials, yet a full immunologic characterization of these vaccines, particularly within the human upper respiratory tract, is less well known. Here, we enumerate and phenotype T cells in nasal mucosa and blood using flow cytometry befor...

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Detalles Bibliográficos
Autores principales: Ssemaganda, Aloysious, Nguyen, Huong Mai, Nuhu, Faisal, Jahan, Naima, Card, Catherine M., Kiazyk, Sandra, Severini, Giulia, Keynan, Yoav, Su, Ruey-Chyi, Ji, Hezhao, Abrenica, Bernard, McLaren, Paul J., Ball, T. Blake, Bullard, Jared, Van Caeseele, Paul, Stein, Derek, McKinnon, Lyle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186487/
https://www.ncbi.nlm.nih.gov/pubmed/35688805
http://dx.doi.org/10.1038/s41467-022-30913-4