Cargando…

Expansion of cytotoxic tissue-resident CD8(+) T cells and CCR6(+)CD161(+) CD4(+) T cells in the nasal mucosa following mRNA COVID-19 vaccination

Vaccines against SARS-CoV-2 have shown high efficacy in clinical trials, yet a full immunologic characterization of these vaccines, particularly within the human upper respiratory tract, is less well known. Here, we enumerate and phenotype T cells in nasal mucosa and blood using flow cytometry befor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ssemaganda, Aloysious, Nguyen, Huong Mai, Nuhu, Faisal, Jahan, Naima, Card, Catherine M., Kiazyk, Sandra, Severini, Giulia, Keynan, Yoav, Su, Ruey-Chyi, Ji, Hezhao, Abrenica, Bernard, McLaren, Paul J., Ball, T. Blake, Bullard, Jared, Van Caeseele, Paul, Stein, Derek, McKinnon, Lyle R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186487/ https://www.ncbi.nlm.nih.gov/pubmed/35688805 http://dx.doi.org/10.1038/s41467-022-30913-4

Ejemplares similares

Endothelial Cells Promote Productive HIV Infection of Resting CD4(+) T Cells by an Integrin-Mediated Cell Adhesion-Dependent Mechanism
por: Card, Catherine M., et al.
Publicado: (2022)

CD161-Expressing Human T Cells
por: Fergusson, Joannah R., et al.
Publicado: (2011)

Percentages of CD4+CD161+ and CD4−CD8−CD161+ T Cells in the Synovial Fluid Are Correlated with Disease Activity in Rheumatoid Arthritis
por: Miao, Jinlin, et al.
Publicado: (2015)

Endocervical Regulatory T Cells Are Associated With Decreased Genital Inflammation and Lower HIV Target Cell Abundance
por: Ssemaganda, Aloysious, et al.
Publicado: (2021)

P16-15. Epitope mapping of HIV-specific CD8+ T-cells responses by polyfunctional and proliferation responses reveal distinct specificity defined by function
por: Richmond, ME, et al.
Publicado: (2009)

Interferon Regulatory Factor 1 Polymorphisms Previously Associated with Reduced HIV Susceptibility Have No Effect on HIV Disease Progression
por: Sivro, Aida, et al.
Publicado: (2013)

CD161+ regulatory t cells in immune regulation
por: Duurland, Chantal, et al.
Publicado: (2014)

Identification of Cytolytic CD161(−)CD56(+) Regulatory CD8 T Cells in Human Peripheral Blood
por: Hu, Dan, et al.
Publicado: (2013)

Association Between Impaired Vα7.2+CD161++CD8+ (MAIT) and Vα7.2+CD161-CD8+ T-Cell Populations and Gut Dysbiosis in Chronically HIV- and/or HCV-Infected Patients
por: Merlini, Esther, et al.
Publicado: (2019)

CD161(+) Tconv and CD161(+) Treg Share a Transcriptional and Functional Phenotype despite Limited Overlap in TCRβ Repertoire
por: Duurland, Chantal L., et al.
Publicado: (2017)

CD8(+)CD161(+) T-Cells: Cytotoxic Memory Cells With High Therapeutic Potential
por: Konduri, Vanaja, et al.
Publicado: (2021)

Differential Effect of Cytomegalovirus Infection with Age on the Expression of CD57, CD300a, and CD161 on T-Cell Subpopulations
por: Hassouneh, Fakhri, et al.
Publicado: (2017)

Loss of Circulating CD8+ CD161(high) T Cells in Primary Progressive Multiple Sclerosis
por: Acquaviva, Massimo, et al.
Publicado: (2019)

Frequency of CD4+CD161+ T Cell and Interleukin-10 Expression in Inflammatory Bowel Diseases
por: Tsuchiya, Kazuyo, et al.
Publicado: (2017)

The identification and functional analysis of CD8+PD-1+CD161+ T cells in hepatocellular carcinoma
por: Li, Zhixuan, et al.
Publicado: (2020)

Cytotoxic CD161(−)CD8(+) T(EMRA) cells contribute to the pathogenesis of systemic lupus erythematosus
por: Xiong, Hui, et al.
Publicado: (2023)

LLT1-CD161 Interaction in Cancer: Promises and Challenges
por: Braud, Veronique M., et al.
Publicado: (2022)

Expansion of mixed immune cells using CD3/CD161 co-stimulation for the treatment of cancer
por: Tsumura, Ryo, et al.
Publicado: (2023)

Gene expression profiling identifies candidate biomarkers for new latent tuberculosis infections. A cohort study
por: Herrera, Mariana, et al.
Publicado: (2022)

Proportion of Ugandans with pre-pandemic SARS-CoV-2 cross-reactive CD4+ and CD8+ T-cell responses: A pilot study
por: Namuniina, Annemarie, et al.
Publicado: (2023)

CD161(int) CD8+ T cells: a novel population of highly functional, memory CD8+ T cells enriched within the gut
por: Fergusson, J.R., et al.
Publicado: (2015)

Circulating CD3(+)CD4(+)CD161(+) Cells Are Associated with Early Complications after Autologous Stem Cell Transplantation in Multiple Myeloma
por: Lee, Sung-Eun, et al.
Publicado: (2018)

The loss of CCR6+ and CD161+ CD4+ T cell homeostasis contributes to disease progression in SIV-infected rhesus macaques
por: McGary, Colleen S., et al.
Publicado: (2017)

Human interleukin 17–producing cells originate from a CD161(+)CD4(+) T cell precursor
por: Cosmi, Lorenzo, et al.
Publicado: (2008)

A CD4+CD161+ T-Cell Subset Present in Unexposed Humans, Not Tb Patients, Are Fast Acting Cells That Inhibit the Growth of Intracellular Mycobacteria Involving CD161 Pathway, Perforin, and IFN-γ/Autophagy
por: Yang, Rui, et al.
Publicado: (2021)

Impact of Aging on the Frequency, Phenotype, and Function of CD161-Expressing T Cells
por: van der Geest, Kornelis S. M., et al.
Publicado: (2018)

CD161 expression defines new human γδ T cell subsets
por: Karunathilaka, Amali, et al.
Publicado: (2022)

CD161(+)CD4(+) T cells are enriched in the liver during chronic hepatitis and associated with co-secretion of IL-22 and IFN-γ
por: Kang, Yu-Hoi, et al.
Publicado: (2012)

The Clinical Relevance of IL-17-Producing CD4+CD161+ Cell and Its Subpopulations in Primary Sjögren's Syndrome
por: Li, Linbo, et al.
Publicado: (2015)

Effect of CMV and Aging on the Differential Expression of CD300a, CD161, T-bet, and Eomes on NK Cell Subsets
por: Lopez-Sejas, Nelson, et al.
Publicado: (2016)

Clinical significance of CD161(+)CD4(+) T cells in the development of chronic antibody-mediated rejection in kidney transplant recipients
por: Kim, Kyoung Woon, et al.
Publicado: (2018)

Enhanced Th1/Th17 Functions of CD161(+) CD8(+) T Cells in Mucosal Tissues of Rhesus Macaques
por: Rout, Namita
Publicado: (2016)

Airway CD8(+)CD161(++)TCRvα7.2(+) T Cell Depletion During Untreated HIV Infection Targets CD103 Expressing Cells
por: Mvaya, Leonard, et al.
Publicado: (2019)

Low Levels of Peripheral CD161++CD8+ Mucosal Associated Invariant T (MAIT) Cells Are Found in HIV and HIV/TB Co-Infection
por: Wong, Emily B., et al.
Publicado: (2013)

Tranilast, an analogue of tryptophan catabolites, induces allograft tolerance by CD161(+) cells
por: Ménoret, Séverine, et al.
Publicado: (2011)

Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis
por: Chalan, Paulina, et al.
Publicado: (2015)

Age and CD161 Expression Contribute to Inter-Individual Variation in Interleukin-23 Response in CD8+ Memory Human T Cells
por: Shen, Hui, et al.
Publicado: (2013)

Circulating CD4+CD161+ T Lymphocytes Are Increased in Seropositive Arthralgia Patients but Decreased in Patients with Newly Diagnosed Rheumatoid Arthritis
por: Chalan, Paulina, et al.
Publicado: (2013)

CD161(+) CD4(+) T Cells Harbor Clonally Expanded Replication-Competent HIV-1 in Antiretroviral Therapy-Suppressed Individuals
por: Li, Xiaomin, et al.
Publicado: (2019)

Diminished HIV Infection of Target CD4+ T Cells in a Toll-Like Receptor 4 Stimulated in vitro Model
por: Cromarty, Ross, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5iiplhjt1557ek1h3cqmr24l7s