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MRTF-A-mediated protection against amyloid-β-induced neuronal injury correlates with restoring autophagy via miR-1273g-3p/mTOR axis in Alzheimer models

Myocardia-Related Transcription Factors-A (MRTF-A), which is enriched in the hippocampus and cerebral cortex, has been shown to have a protective function against ischemia hypoxia-induced neuronal apoptosis. However, the function of MRTF-A on β-amyloid peptide (Aβ)-induced neurotoxicity and autophag...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Yang, Yuewang, Xiang, Zifei, Cheng, Jinping, Yu, Zhijun, Wang, Wen, Hu, Ling, Ma, Fuyun, Deng, Youping, Jin, Zhigang, Hu, Xiamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9186769/
https://www.ncbi.nlm.nih.gov/pubmed/35604830
http://dx.doi.org/10.18632/aging.203883