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Alpha-synuclein and tau are abundantly expressed in the ENS of the human appendix and monkey cecum

α-Synuclein (α-syn) proteinopathy in the neurons of the Enteric Nervous System (ENS) is proposed to have a critical role in Parkinson’s disease (PD) onset and progression. Interestingly, the ENS of the human appendix harbors abundant α-syn and appendectomy has been linked to a decreased risk and del...

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Detalles Bibliográficos
Autores principales: Zinnen, Alexandra D., Vichich, Jonathan, Metzger, Jeanette M., Gambardella, Julia C., Bondarenko, Viktoriya, Simmons, Heather A., Emborg, Marina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187115/
https://www.ncbi.nlm.nih.gov/pubmed/35687573
http://dx.doi.org/10.1371/journal.pone.0269190