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Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies

Sprague Dawley (SD) rats are among the most widely used outbred laboratory rat populations. Despite this, the genetic characteristics of SD rats have not been clearly described, and SD rats are rarely used for experiments aimed at exploring genotype-phenotype relationships. In order to use SD rats t...

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Detalles Bibliográficos
Autores principales: Gileta, Alexander F., Fitzpatrick, Christopher J., Chitre, Apurva S., St. Pierre, Celine L., Joyce, Elizabeth V., Maguire, Rachael J., McLeod, Africa M., Gonzales, Natalia M., Williams, April E., Morrow, Jonathan D., Robinson, Terry E., Flagel, Shelly B., Palmer, Abraham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187121/
https://www.ncbi.nlm.nih.gov/pubmed/35639796
http://dx.doi.org/10.1371/journal.pgen.1010234