Structural insights into G protein activation by D1 dopamine receptor

G protein–coupled receptors (GPCRs) comprise the largest family of membrane receptors and are the most important drug targets. An agonist-bound GPCR engages heterotrimeric G proteins and triggers the exchange of guanosine diphosphate (GDP) with guanosine triphosphate (GTP) to promote G protein activ...

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Detalles Bibliográficos
Autores principales: Teng, Xiao, Chen, Sijia, Wang, Qing, Chen, Zhao, Wang, Xiaoying, Huang, Niu, Zheng, Sanduo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187227/
https://www.ncbi.nlm.nih.gov/pubmed/35687690
http://dx.doi.org/10.1126/sciadv.abo4158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187227/
https://www.ncbi.nlm.nih.gov/pubmed/35687690
http://dx.doi.org/10.1126/sciadv.abo4158

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