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Promotion of row 1–specific tip complex condensates by Gpsm2-Gαi provides insights into row identity of the tallest stereocilia

The mechanosensory stereocilia in hair cells are organized into rows of graded height, a property crucial for auditory perception. Gpsm2-Gαi-Whirlin-Myo15-Eps8 complex at tips of the tallest stereocilia is proposed to define hair bundle row identity, although the underlying mechanism remains elusive...

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Detalles Bibliográficos
Autores principales: Shi, Yingdong, Lin, Lin, Wang, Chao, Zhu, Jinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187228/
https://www.ncbi.nlm.nih.gov/pubmed/35687681
http://dx.doi.org/10.1126/sciadv.abn4556