Single-cell analysis of human basal cell carcinoma reveals novel regulators of tumor growth and the tumor microenvironment

How basal cell carcinoma (BCC) interacts with its tumor microenvironment to promote growth is unclear. We use singe-cell RNA sequencing to define the human BCC ecosystem and discriminate between normal and malignant epithelial cells. We identify spatial biomarkers of tumors and their surrounding str...

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Detalles Bibliográficos
Autores principales: Guerrero-Juarez, Christian F., Lee, Gun Ho, Liu, Yingzi, Wang, Shuxiong, Karikomi, Matthew, Sha, Yutong, Chow, Rachel Y., Nguyen, Tuyen T. L., Iglesias, Venus Sosa, Aasi, Sumaira, Drummond, Michael L., Nie, Qing, Sarin, Kavita, Atwood, Scott X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187229/
https://www.ncbi.nlm.nih.gov/pubmed/35687691
http://dx.doi.org/10.1126/sciadv.abm7981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187229/
https://www.ncbi.nlm.nih.gov/pubmed/35687691
http://dx.doi.org/10.1126/sciadv.abm7981

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