Cargando…

Metformin Ameliorates Senescence of Adipose-Derived Mesenchymal Stem Cells and Attenuates Osteoarthritis Progression via the AMPK-Dependent Autophagy Pathway

Osteoarthritis (OA) is one of the most serious age-related diseases worldwide that drastically affects the quality of life of patients. Despite advancements in the treatment of arthritis, especially with adipose-derived mesenchymal stem cells (ADSCs), senescence-induced alterations in ADSCs negative...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Zheng, Liu, Lin, Yang, Yanni, Zheng, Haishi, Cai, Yongsong, Ma, Yao, Gu, Ruiying, Xu, Ke, Zhang, Rui, Xu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187432/
https://www.ncbi.nlm.nih.gov/pubmed/35693701
http://dx.doi.org/10.1155/2022/4620254